Ariser

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Overview

Ariser (Adjuvant Rencarex Immunotherapy trial to Study Efficacy in non-metastasized Renal cell carcinoma), being a Trial of the drug RENCAREX® produced by Wilex AG.

Details

About the Ariser study

The international, multicentre, randomised trial, called Ariser (Adjuvant Rencarex Immunotherapy trial to Study Efficacy in non-metastasized Renal cell carcinoma), examines the efficacy of the antibody RENCAREX® in comparison to placebo for the treatment of clear cell renal cell cancer patients after complete or partial surgical removal of the affected kidney in patients with no detectable metastases. This cancer belongs to one of the particularly aggressive indications. RENCAREX® aims to inhibit these malignant kidney tumours from further growth and recurrence and to help to destroy cancer cells and thereby prolong the disease-free survival of patients. The study is designed to detect a 35% improvement of disease-free survival time in patients treated with RENCAREX® compared to patients treated with placebo with a statistical significance of 1%.

References

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