CA9-SCAN
From Kidney Cancer Resource
Contents |
Overview
CA9-SCAN is produced by Wilex
CA9-SCAN is an investigational imaging diagnostic based on an antibody and is being developed for the pre-surgical diagnosis of clear cell Renal Cell Cancer. CA9-SCAN is the radioactively labelled form of the antibody WX-G250. The labelled antibody WX-G250 targets clear cell renal cell carcinoma and accumulates in the tumour tissue. This accumulation can be visualised by means of Positron Emission Tomography (PET). An earlier feasibility study found that a positive result with CA9-SCAN was confirmed as clear cell renal cell carcinoma in 100% of cases (positive predictive value). CA9-SCAN could determine whether the patient had clear cell renal cell carcinoma before surgery and the subsequent pathology. Therefore, CA9-SCAN could significantly improve and simplify treatment planning for patients suspected of having renal cancer. The company is not aware of any other available imaging technique with comparable specificity and sensitivity.
About CA9-SCAN (more)
CA9-SCAN is one of two product candidates from WILEX's late stage multi-product portfolio which is in a Phase III registration trial. CA9-SCAN is a radioactively labelled form of the antibody WX-G250. The labelled antibody WX-G250 targets clear cell renal cell carcinoma and accumulates in the tumour tissue. This accumulation can be visualised by means of Positron Emission Tomography (PET) / Computer Tomography (CT). An earlier feasibility study found that a positive result with CA9-SCAN was confirmed as clear cell renal cell carcinoma in 100% of cases (positive predictive value). CA9-SCAN could determine whether the patient had clear cell renal cell carcinoma before surgery and the subsequent pathology. Therefore, CA9-SCAN could improve treatment planning for patients suspected of having renal cancer.
References
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